A United States pharmacopeia chapter 800-centered process improvement proposal for compounding antineoplastic medications in an academic medical center pharmacy

Veronica Bonderski, Mary Clay, Raoof Abdellatif

Abstract


It is well described that handling antineoplastic medications without proper personal and environmental protections leads to malignancy, reproductive toxicity, and organ damage. In December 2019, the United States Pharmacopeia Chapter 800 (USP<800>), which addresses the proper handling of hazardous drugs, will be enforceable for any facility handling these agents. Northwestern Memorial Hospital in Chicago, Illinois has developed a process improvement for the central pharmacy clean room to increase compliance to USP<800> standards. This plan specifically focuses on adjusting the workflow of four antineoplastic agents that are compounded in their central pharmacy clean room.


Keywords


United States Pharmacopeia chapter 800; pharmacy; antineoplastic; National Institute for Occupational Safety and Health; compliance

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References


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