Frequency of genito-urinary tract disorders in a tertiary hospital in Isfahan, Iran
Keywords:
Urolithiasis, prostate, clustering, hyperplasia, genito-urinary, malignant, penisAbstract
For advanced planning related to health issues for hospitalized patients, we aimed to categorize genitourinary tract disorders in a large, representative sample of patients' population in a referral teaching hospital in Isfahan, Iran. In this retrospective study, we enrolled 3721 patients of both genders with a mean age of 45 (ranged from 1 to 93) years old. Clinical and demographical data were recorded in Excel. The statistical analyses processed using SPSS for windows. 79% of total population were males and in the 58% age ranged from 20 to 60 years old that was correlated to employed years of life. In the 78% complications related to genitourinary tract disorders ranked as: urolithiasis (n = 27%), prostate (n = 17%), kidney (n = 14%), testis (n = 11%) and bladder (n = 9%). In the residual 22% of population classified disorders were as: penis, urethral stricture, inguinal hernia, vesicoureteral reflux, urinary incontinence, cystocele, renal colic and adrenal gland. In the 528 patients classified kidney disorders were ranked as: ESRD (51%), unknown kidney disease (38%), malignant neoplasm (7%), and cystic kidney (6%). Testis disorders classified as varicocele (40%), testicular torsion (23%), cryptorchidism (16%), and hydrocele (10%). This study confirmed that among a group of genitourinary tract disorders, the frequency of urolithiasis and prostate were higher than others. The percentage of males with genitourinary tract disorders was higher than females. Among testis disorders varicocele and testicular torsion was high. In the more than of half studied patients’ age was related to active and working years of lifetime. Finally as the occurrence of urolithiasis and prostate disorders is increasing in Isfahan, further research in these directions seems to be advantageous.
References
Hostetter TH. Chronic Kidney Disease Predicts Cardiovascular Disease. New Engl J Med 351:1344–1346, 2004.
Tolou-Ghamari Z. Investigation of final causes of death in 5360 deceased patients within a teaching hospital in Isfahan, Iran. Am J Exp Clin Res 3:161-164, 2016.
Grantham J. Pathogenesis of Autosomal Dominant Polycystic Kidney Disease: Recent Developments. In: Hereditary Kidney Diseases, ed. A. Sessa, F. Conte, M. Meroni, and G. Battini. Contributions to Nephrology. Basel, Switzerland: Karger vol. 122:1-9, 1997.
Stengel B, Billon S, van Dijk P, Jager K et al. Trends in the incidence of renal replacement therapy for end-stage renal disease in Europe, 1990-1999. Nephrol Dial Transplant 18:1824-1833, 2003.
Suskind AM, Saigal CS, Hanley JM, et al. Urologic Diseases of America Project. Incidence and management of uncomplicated recurrent urinary tract infections in a national sample of women in the United States. Urology 90:50-55, 2016.
Hooton T. Urinary Tract Infections in Adults. In: Comprehensive Clinical Nephrology, ed. R. J. Johnson and J Feehally. London: Mosby 56.1-12, 2000.
Barsoum RS. End-Stage Renal Disease in North Africa. Kidney Int 63:S111–114, 2003.
Morton AR, Iliescu EA, Wilson JW. Nephrology: "Investigation and Treatment of Recurrent Kidney Stones," Can Med Assoc J 166:213-218, 2002.
Hussain M, Lai M, Ali B, Ahmed S, Zafar N, Naqvi A, Rizvi A. Management of urinary calculi associated with renal failure. J Pakistan Med Assoc 45:205-208, 1996.
Spradling K, Vernez SL, Khoyilar C, et al. Prevalence of hyperoxaluria in urinary stone formers: Chronological and geographical trends and a literature review. J Endourol 30:469-475, 2016.
Garcia Nieto V, Huertes Díaz B, Escribano Subias J, Alarcón Alacio MT, Gonzalez Rodríguez JD et al. Unilateral renal agenesis. New arguments about the genetic relationship between kidney malformations and urolithiasis. An Pediatr (Barc) 85:240-246, 2016.
La Vecchia C, Levi F, Lucchini F. Mortality from benign prostatic hyperplasia: Worldwide trends 1950-92. J Epidemiol Community Health 49:379-384, 1995.
Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA et al. Prostate cancer susceptibility in men of African ancestry at 8q24. J Natl Cancer Inst 108: djv431, 2016.
Frassetto L, Kohlstadt I. Treatment and prevention of kidney stones: an update. Am Fam Physician 84:1234-1242, 2011.
Coe Fl, Evan A, Worcester E. Kidney stone disease. J Clin Invest 115:2598-2608, 2005.
Pickard R, Starr K, MacLennan G, et al. Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. Lancet 386:341-349, 2015.
Mukesh V, Payal P and Mudit V. Biomarkers in prostate cancer epidemiology. Cancers (Basel) 3: 3773-3798, 2011.
Chornokur G, Dalton K, Borysova ME, Kumar NB. Disparities at presentation, diagnosis, treatment, and survival in African American men, affected by prostate cancer. Prostate 71: 985-997, 2011.
Gurel B, Lucia MS, Thompson IM Jr, et al. Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer Epidemiol Biomarkers Prev 23:847-856, 2014.
Kim DH, Kim M, Kim H, Kim YL, Kang SW, Yang CW, Kim NH, Kim YS, Lee JP. Early referral to a nephrologist improved patient survival: prospective cohort study for end-stage renal disease in Korea. PLoS One 8:e55323, 2013.
Serrano T, Chevrier C, Multigner L, Cordier S, Jégou. International geographic correlation study of the prevalence of disorders of male reproductive health. Hum Reprod 2013 28:1974-1986, 2013.
Levine L, Rybak J, Corder C, Farrel MR. Peyronie's disease plaque calcification-prevalence, time to identification, and development of a new grading classification. J Sex Med 10:3121-3128, 2013.
Shaeer O. Torsion of the penis in adults: prevalence and surgical correction. J Sex Med 5:735-739, 2008.
Hatipoğlu NI, S Kurtoğlu. Micropenis: Etiology, diagnosis and treatment approaches. J Clin Res Pediatr Endocrinol 5: 217-223, 2013.
Nygaard I, Barber MD, Burgio K. Prevalence of symptomatic pelvic floor disorders in US women JAMA 300: 1311-1316, 2010.
Yazdani M, Tolou-Ghamari Z, Asadi-Samani M, Mazdak H, Yazdani E. Investigation of prostate disorders in 614 patients attended Alzahra urology ward between the years 2013 to 2015 in Isfahan. Int J Pharm Clin Res 8: 1543-1547, 2016.
Tolou-Ghamari Z, Mehavari-Habibabadi J, Palizban AA. Evidence based pharmacotherapy of epilepsy. Arch Neuroscience 2: e18468.
Tolou-Ghamari Z, Najafi MR, Mehavari Habibabadi J, Zare M. Preliminarily analysis of carbamazepine (CBZ) C0 in patients visited Isfahan epileptic clinics. Int J Prev Med S343-346, 2013.
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