Survival and Clinicopathologic characteristics of Meningioma

Mehrdad Roozbeh, Shokouh Taghipour zahir, Mahrooz Roozbeh, Farzan SafiDahaj


Objectives: With the prevalence of one-third of intracranial brain tumors, Meningioma prognosis is affected by the size, location, ability to access the tumor through surgery, and the degree of histological malignancy. We intended to investigate patients' prognosis and clinical features with central nervous system meningioma.


Materials and Methods: Records of all patients with central nervous system and spinal cord meningiomas between 2006-2016 in Yazd Shahid Sadoughi, Shahid Rahnemoun, Mortaz, Goodarz, and Mojibian hospitals were studied. Using SPSS version 17, survival, age, type of treatment, grade, size, and tumor location were investigated in this retrospective cross-sectional study.


Results: Of the 175 patients (66 (37.7%) male, 109 (62.3%) female) with an average survival time of 78.5 months, tumors recurred in 12 (10.7%) patients. Among them, 63 (47%) were between 18-54, and 72 (53%) were between 55-87 years. Syncytial was the most common histological subtype, and a significant relationship between age and tumor subtype was found (p-value = 0.03). Primary symptoms of headache and nausea/vomiting were in most of them (51, 57%). The most and the most minor expected location was the brain lobes (14 cases) and the spinal cord (2 patients). There was no significant relationship between meningioma subtype-symptoms, survival-gender/ tumor subtype, recurrence-gender/ age, or tumor subtype. Also, a significant relationship between age and survival was found (p-value = 0.05).


Conclusion: An increase in the prevalence of meningioma in recent years has been due to improvements in imaging techniques and the population's aging. Overall, there was a significant relationship between age and meningioma prevalence.


Meningioma, brain tumor, survival, recurrence

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