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A novel experimental and clinical research on pathogenic and cellular mechanisms, transmission, diagnostic and clinical treatment of COVID–19 infection
Abstract
Coronaviruses are a large family of viruses that cause a variety of illnesses, from the common cold to severe acute respiratory syndrome. The SARS–COV–2 outbreak was first reported by the World Health Organization in China and has now become an epidemic, reflecting the extremely high transmissibility of the virus, which has caused great concern and stress among people around the world. Research suggests that prevention, risk education, and promotion of self–care behaviors can slow the spread of the disease in communities, and identifying sources of transmission can be effective in controlling it. The mortality rate of this virus is significantly higher in the elderly and people with underlying diseases compared to healthy people. Coronavirus is a challenging disease and can be easily transmitted in public places, and the number of people infected with this virus is increasing exponentially across all ages and groups. Therefore, increasing public awareness of this disease and providing positive psychological programs and teaching prevention methods in the media can reduce mental problems in society, in addition to reducing mortality and the number of patients.
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Heidari A. Fornacite, orotic acid, rhamnetin, sodium ethyl xanthate (SEX) and spermine (spermidine or polyamine) nanomolecules incorporation into the nanopolymeric matrix (NPM). Int J Biochem Biomolecul 4: 1–19, 2018.
Heidari A. Gobato R. Putrescine, cadaverine, spermine and spermidine–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules. Parana J Sci Edu (PJSE) 4:1–14, 2018.
Heidari A. Cadaverine (1,5–pentanediamine or pentamethylenediamine), diethyl azodicarboxylate (DEAD or DEADCAT) and putrescine (tetramethylenediamine) nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations”, hiv and sexual health. Open Access Open J 1: 4–11, 2018.
Heidari A. Improving the performance of nano–endofullerenes in polyaniline nanostructure–based biosensors by covering californium colloidal nanoparticles with multi–walled carbon nanotubes. J Advan Nanomater 3:1–28, 2018.
Gobato R, Heidari A. Molecular mechanics and quantum chemical study on sites of action of sanguinarine using vibrational spectroscopy based on molecular mechanics and quantum chemical calculations. Malaysian J Chem 20: 1–23, 2018.
Heidari A. vibrational biospectroscopic studies on anti–cancer nanopharmaceuticals (part I). Malaysian J Chem 20: 33–73, 2018.
Heidari A. Vibrational biospectroscopic studies on anti–cancer nanopharmaceuticals (part II). Malaysian J Chem 20:74–117, 2018.
Heidari A. Uranocene (U(C8H8)2) and bis(Cyclooctatetraene)Iron (Fe(C8H8)2 or Fe(COT)2)–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules. Chem Reports 1: 1–16, 2018.
Heidari A. “Biomedical systematic and emerging technological study on human malignant and benign cancer cells and tissues biospectroscopic analysis under synchrotron radiation. Glob Imaging Insights 3: 1–7, 2018.
Heidari A. Deep–level transient spectroscopy and x–ray photoelectron spectroscopy (XPS) comparative study on malignant and benign human cancer cells and tissues with the passage of time under synchrotron radiation. Res Dev Material Sci 7(2). RDMS.000659, 2018.
Heidari A. C70–carboxyfullerenes nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Glob Imaging Insights 3: 1–7, 2018.
Heidari A. The effect of temperature on cadmium
oxide (CdO) nanoparticles produced by synchrotron radiation in the human cancer cells, tissues and tumors. Int J Advan Chem 6:140–156, 2018.
Heidari A. A clinical and molecular pathology investigation of correlation spectroscopy (COSY), exclusive correlation spectroscopy (ECOSY), total correlation spectroscopy (TOCSY), heteronuclear single–quantum correlation spectroscopy (HSQC) and heteronuclear multiple–bond correlation spectroscopy (HMBC) comparative study on malignant and benign human cancer cells, tissues and tumors under synchrotron and synchrocyclotron radiations using cyclotron versus synchrotron, synchrocyclotron and the large hadron collider (LHC) for delivery of proton and helium ion (charged particle) beams for oncology radiotherapy. Eur J Advan Engineer Technol 5: 414–426, 2018.
Heidari A. Nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. J Oncol Res; 1: 1–20, 2018.
Heidari A. Use of molecular enzymes in the treatment of chronic disorders. Canc Oncol Open Access J. 1: 12–15, 2018.
Heidari A. Vibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as anti–cancer polymeric nanomedicines using synchrotron radiation. Int J Advan Chem 6:167–189, 2018.
Heidari A. Adamantane, irene, naftazone and pyridine–enhanced precatalyst preparation stabilization and initiation (PEPPSI) nano molecules. Madridge J Nov Drug Res 2: 61–67, 2018.
Heidari A. Heteronuclear single–quantum correlation spectroscopy (HSQC) and heteronuclear multiple–bond correlation spectroscopy (HMBC) comparative study on malignant and benign human cancer cells and tissues with the passage of time under synchrotron radiation. Madridge J Nov Drug Res 2: 68–74, 2018.
Heidari A, Gobato R. A novel approach to reduce toxicities and to improve bioavailabilities of dna/rna of human cancer cells–containing cocaine (Coke), lysergide (lysergic acid diethyl amide or LSD), Δ⁹–tetrahydrocannabinol (THC) [(–)–trans–Δ⁹–tetrahydro-cannabinol], theobromine (Xantheose), caffeine, aspartame (APM) (NutraSweet) and zidovudine (ZDV) [azidothymidine (AZT)] as anti–cancer nano drugs by coassembly of dual anti–cancer nano drugs to inhibit DNA/RNA of human cancer cells drug resistance”, parana journal of science and education (PJSE) 4: 1–17, 2018.
Heidari A, Gobato R. Ultraviolet photoelectron spectroscopy (UPS) and ultraviolet–visible (UV–Vis) spectroscopy comparative study on malignant and benign human cancer cells and tissues with the passage of time under synchrotron radiation. Parana J Sci Edu (PJSE) 4: 18–33, 2018.
Gobato R, Heidari A, Mitra A. The creation of C13H20BeLi2SeSi. The proposal of a bio–inorganic molecule, using ab initio methods for the genesis of a nano membrane. Arc Org Inorg Chem Sci 3 (4) AOICS. MS.ID.000167, 2018.
Gobato R, Heidari A. Using the quantum chemistry for genesis of a nano biomembrane with a combination of the elements Be, Li, Se, Si, C and H”. J Nanomed Res 7:241‒252, 2018.
Heidari A. Bastadins and bastaranes–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules. Glob Imag Insights 3: 1–7, 2018.
Heidari A. Fucitol, Pterodactyladiene, DEAD or DEADCAT (DiEthyl AzoDiCArboxylaTe), Skatole, the NanoPutians, Thebacon, Pikachurin, Tie Fighter, Spermidine and Mirasorvone nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under Synchrotron and Synchrocyclotron radiations. Glob Imag Insights 3(4): 1–8, 2018.
Dadvar E, Heidari A. A Review on separation techniques of graphene oxide (GO)/base on hybrid polymer membranes for eradication of dyes and oil compounds: recent progress in graphene oxide (GO)/base on polymer membranes–related nanotechnologies. Clin Med Rev Case Rep 5: 228, 2018.
Heidari A, Gobato R. First–time simulation of deoxyuridine monophosphate (dUMP) (Deoxyuridylic acid or Deoxyuridylate) and Vomitoxin (Deoxynivalenol (DON)) ((3α,7α)–3,7,15–trihydroxy–12,13–epoxytricho-thec–9–En–8–One)–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human
cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Parana J Sci Edu (PJSE) 4(6): 46–67, 2018.
Heidari A. Buckminsterfullerene (Fullerene), Bullvalene, Dickite and Josiphos Ligands nano molecules incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human hematology and thromboembolic diseases prevention, diagnosis and treatment under synchrotron and synchrocyclotron radiations. Glob Imag Insights 3(4): 1–7, 2018.
Heidari A. Fluctuation x–ray scattering (FXS) and Wide–angle x–ray scattering (WAXS) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imag Insights 3(4): 1–7, 2018.
Heidari A. A Novel approach to correlation spectroscopy (COSY), exclusive correlation spectroscopy (ECOSY), total correlation spectroscopy (TOCSY), incredible natural–abundance double–quantum transfer experiment (INADEQUATE), heteronuclear single–quantum correlation spectroscopy (HSQC), heteronuclear multiple–bond correlation spectroscopy (HMBC), nuclear overhauser effect spectroscopy (NOESY) and rotating frame nuclear overhauser effect spectroscopy (ROESY) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imag Insights 3(5): 1–9, 2018.
Heidari A. Terphenyl–based reversible receptor with rhodamine, rhodamine–based molecular probe, rhodamine–based using the spirolactam ring opening, rhodamine b with ferrocene substituent, calix[4]arene–based receptor, thioether + aniline–derived ligand framework linked to a fluorescein platform, mercuryfluor–1 (flourescent probe), N,N’–dibenzyl–1,4,10,13–tetraraoxa–7,16–diazacyclooctadecane and terphenyl–based reversible receptor with pyrene and quinoline as the fluorophores–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules. Glob Imag Insights 3(5): 1–9, 2018.
Heidari A. Small–angle x–ray scattering
(saxs), ultra–small angle x–ray scattering (USAXS), fluctuation x–ray scattering (FXS), wide–angle x–ray scattering (WAXS), grazing–incidence small–angle x–ray scattering (GISAXS), grazing–incidence wide–angle x–ray scattering (GIWAXS), small–angle neutron scattering (SANS), grazing–incidence small–angle neutron scattering (GISANS), x–ray diffraction (XRD), powder x–ray diffraction (PXRD), wide–angle x–ray diffraction (WAXD), grazing– incidence x–ray diffraction (GIXD) and energy–dispersive x–ray diffraction (EDXRD) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imag Insights 3(5): 1–10, 2018.
Heidari A. Nuclear resonant inelastic x–ray scattering spectroscopy (NRIXSS) and nuclear resonance vibrational spectroscopy (NRVS) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imaging Insights 3: 1–7, 2018.
Heidari A. Small–angle x–ray scattering (SAXS)
and ultra–small angle x–ray scattering (USAXS) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imaging Insights 3: 1–7, 2018.
Heidari A. Curious chloride (CmCl3) and titanic chloride (TiCl4)–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules for cancer treatment and cellular therapeutics. J. Cancer Res Ther Intervent 1: 01–10, 2018.
Gobato R, Gobato MRR, Heidari A, Mitra A. Spectroscopy and dipole moment of the molecule C13H20BeLi2SeSi via quantum chemistry using Ab initio, Hartree–Fock method in the base set CC–pVTZ and 6–311G**(3df, 3pd). Arc Org Inorg Chem Sci 3:402–409, 2018.
Heidari A. C60 and C70–encapsulating carbon nanotubes incorporation into the nano polymeric matrix (NPM) by immersion of the nano polymeric modified electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Integr Mol Med 5: 1–8, 2018.
A. Heidari, “Two–Dimensional (2D) 1H or Proton NMR, 13C NMR, 15N NMR and 31P NMR Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights, Volume 3 (6): 1–8, 2018.
A. Heidari, “FT–raman spectroscopy, coherent anti–stokes raman spectroscopy (CARS) and raman optical activity spectroscopy (ROAS) comparative study on malignant and benign human cancer cells and tissues with the passage of time under synchrotron radiation. Glob Imaging Insights 3: 1–8, 2018.
Heidari A. A Modern and comprehensive investigation of inelastic electron tunneling spectroscopy (IETS) and scanning tunneling spectroscopy on malignant and benign human cancer cells, tissues and tumors through optimizing synchrotron microbeam radiotherapy for human cancer treatments and diagnostics: An experimental biospectroscopic comparative study. Glob Imaging Insights, Volume 3 (6): 1–8, 2018.
Heidari A. A hypertension approach to thermal infrared spectroscopy and photothermal infrared spectro-scopy comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation with the passage of time. Glob Imag Insights 3(6): 1–8, 2018.
Heidari A. Incredible natural–abundance double–quantum transfer experiment (INADEQUATE), nuclear overhauser effect spectroscopy (NOESY) and rotating frame nuclear overhauser effect spectroscopy (ROESY) comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Glob Imag Insights 3(6): 1–8, 2018.
Heidari A. 2–Amino–9–((1S, 3R, 4R)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One, 2–Amino–9–((1R, 3R, 4R)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One, 2–Amino–9–((1R, 3R, 4S)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One and 2–Amino–9–((1S, 3R, 4S)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One–Enhanced Precatalyst Preparation Stabilization and Initiation Nano Molecules. Glob Imaging Insights 3: 1–9, 2018.
Gobato R, Gobat MRR, Heidari A, Mitra A. Spectroscopy and dipole moment of the molecule C13H20BeLi2SeSi via quantum chemistry using Ab Initio, Hartree–Fock method in the base set CC–pVTZ and 6–311G**(3df, 3pd). Am J Quantum Chem Molcul Spectroscop 2:9–17, 2018.
Heidari A. Production of electrochemilumine-scence (ECL) biosensor using Os–Pd/HfC nano-composites for detecting and tracking of human gastroenterological cancer cells, tissues and tumors. Int J Med Nano Res 5:022–034, 2018.
Heidari A. Enhancing the Raman scattering for diagnosis and treatment of human cancer cells, tissues and tumors using cadmium oxide (CdO) nanoparticles. J Toxicol Risk Assess 4: 1, 012–025, 2018.
Heidari A. Human malignant and benign human cancer cells and tissues biospectroscopic analysis under synchrotron radiation using anti–cancer nano drugs delivery. Integr Mol Med, Volume 5: 1–13, 2018.
heidari a. analogous nano compounds of the form M(C8H8)2 exist for M = (Nd, Tb, Pu, Pa, Np, Th, and Yb)–enhanced precatalyst preparation stabilization and initiation (EPPSI) nano molecules. Integr Mol Med, Volume 5 (5): 1–8, 2018.
Heidari A. Hadron spectroscopy, baryon spectroscopy and meson spectroscopy comparative study on malignant and benign human cancer cells and tissues under synchrotron radiation. Integr Mol Med 5: 1–8, 2018.
Gobato R, Gobato MRR, Heidari A. Raman spectroscopy study of the nano molecule C13H20BeLi2SeSi using ab initio and Hartree–Fock methods in the basis set CC–pVTZ and 6–311G** (3df, 3pd). Int J Adv Engineer Sci 7:14–35, 2019.
Heidari A, Gobato R. “Evaluating the effect of anti–cancer nano drugs dosage and reduced leukemia and polycythemia vera levels on trend of the human blood and bone marrow cancers under synchrotron radiation.” Trends Res 2: 1–8, 2019.
Heidari A, Gobato R. Assessing the variety of synchrotron, synchrocyclotron and LASER radiations and their roles and applications in human cancer cells, tissues and tumors diagnosis and treatment. Trends Res 2:1 8, 2019.
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